Huseyin Naci , Jasper Jan Brugts and Tony Ades
نویسندگان
چکیده
منابع مشابه
Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials.
BACKGROUND Our objective was to estimate the comparative harms of individual statins using both placebo-controlled and active-comparator trials. METHODS AND RESULTS We systematically reviewed randomized trials evaluating different statins in participants with and without cardiovascular disease. We performed random-effects pairwise and network meta-analyses to quantify the relative harms of in...
متن کاملComparative Tolerability and Harms of Individual Statins
S tatins are widely used to prolong survival and reduce the occurrence of coronary and cerebrovascular events in patients with and without cardiovascular disease. Prior meta-analyses have demonstrated the effectiveness of statins for the primary and secondary prevention of cardiovascular disease , 1–5 with consistent benefits across subgroups, including the elderly, 6 women, 7 and individuals w...
متن کاملEvidence-based prescribing: combining network meta-analysis with multicriteria decision analysis to choose among multiple drugs.
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. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . doi:10.1093/ehjci/jer229 Online publish-ahead-of-pr...
متن کاملComparative effects of statins on major cerebrovascular events: a multiple-treatments meta-analysis of placebo-controlled and active-comparator trials.
Statins are important in the prevention of major cerebrovascular events. Whether, and the extent to which, individual statins differ in terms of their effect on these outcomes has not been studied. The aim of this review was to evaluate the comparative effects of individual statins on major cerebrovascular events. We systematically reviewed 61 trials including 187 038 individuals with, or at ri...
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